GraphPad Prism v5.01 serial key or number

GraphPad Prism v5.01 serial key or number

GraphPad Prism v5.01 serial key or number

GraphPad Prism v5.01 serial key or number


Graph Pad Software Incceftazidime


https://www.bioz.com/result/ceftazidime/product/Graph Pad Software Inc
Average 92 stars, based on 3600 article reviews
Price from $9.99 to $1999.99
ceftazidime - by Bioz Stars, 2020-09

Related Products / Commonly Used Together


1) Product Images from "In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays"

Article Title: In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays

Journal: Antimicrobial Agents and Chemotherapy

doi: 10.1128/AAC.04146-14


Figure Legend Snippet: Cumulative % inhibition of 18 P. aeruginosa isolates by ceftazidime for increasing concentrations (symbols below the figure, mg/liter) of avibactam. The % inhibition of growth of P. aeruginosa is presented on the y axis with the MIC for ceftazidime on the x axis as related to the added concentrations of avibactam in differently colored lines.

Techniques Used: Inhibition

2) Product Images from "Defining and Systematic Analyses of Aggregation Indices to Evaluate Degree of Calcium Oxalate Crystal Aggregation"

Article Title: Defining and Systematic Analyses of Aggregation Indices to Evaluate Degree of Calcium Oxalate Crystal Aggregation

Journal: Frontiers in Chemistry

doi: 10.3389/fchem.2017.00113


Figure Legend Snippet: COM crystal aggregation indices derived from GraphPad Prism6 software. Rationales of defining aggregation indices from GraphPad Prism6 software are illustrated in (A,B) . Quantitative analysis using GraphPad Prism6 software revealed four additional aggregation indices, including rate constant (C) , half-life (D) , span (E) , and time constant (F) . Each bar represents mean ± SEM of the data obtained from 3 independent experiments. A.U., arbitrary unit. * p

Techniques Used: Derivative Assay, Software

3) Product Images from "A Mutant of Sindbis Virus Which Is Able To Replicate in Cells with Reduced CTP Makes a Replicase/Transcriptase with a Decreased Km for CTP"

Article Title: A Mutant of Sindbis Virus Which Is Able To Replicate in Cells with Reduced CTP Makes a Replicase/Transcriptase with a Decreased Km for CTP

Journal: Journal of Virology

doi: 10.1128/JVI.78.18.9645-9651.2004


Figure Legend Snippet: Kinetic analyses of in vitro viral RNA synthesis by the SV CPC and SV STD replicase/transcriptases. The assays were performed with p15 fractions from virus-infected mosquito cells as described in Materials and Methods. Nonlinear regression analysis with the GraphPad Prism version 3.0 software was used to calculate the K m s of the SV polymerase for CTP (A) and UTP (B). Each reaction was done in triplicate.

Techniques Used: In Vitro, Infection, Software

4) Product Images from "Defining and Systematic Analyses of Aggregation Indices to Evaluate Degree of Calcium Oxalate Crystal Aggregation"

Article Title: Defining and Systematic Analyses of Aggregation Indices to Evaluate Degree of Calcium Oxalate Crystal Aggregation

Journal: Frontiers in Chemistry

doi: 10.3389/fchem.2017.00113


Figure Legend Snippet: COM crystal aggregation indices derived from GraphPad Prism6 software. Rationales of defining aggregation indices from GraphPad Prism6 software are illustrated in (A,B) . Quantitative analysis using GraphPad Prism6 software revealed four additional aggregation indices, including rate constant (C) , half-life (D) , span (E) , and time constant (F) . Each bar represents mean ± SEM of the data obtained from 3 independent experiments. A.U., arbitrary unit. * p

Techniques Used: Derivative Assay, Software

5) Product Images from "The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver"

Article Title: The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver

Journal: British Journal of Clinical Pharmacology

doi: 10.1046/j.1365-2125.2002.01614.x


Figure Legend Snippet: Spearman rank correlation between CYP2C9 (a), CYP2D6 (b), CYP2B6 (c) and CYP3A4 (d) expression (pmol mg −1 protein) and formation rate of Z-4-OH-tamoxifen ( V , pmol mg −1 protein min −1 ) in human liver microsomes ( n = 50).

Techniques Used: Expressing

6) Product Images from "Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57"

Article Title: Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

Journal: Scientific Reports

doi: 10.1038/s41598-018-28172-9


Figure Legend Snippet: Tizoxanide inhibits ERp57 activity. ( A ) Domain organization ( top ) and surface representation ( bottom ) of ERp57. ( B ) Effect of tizoxanide (10 and 50 μg/ml) on ERp57 disulfide reductase activity, determined by the insulin reduction turbidometric assay, as described in Methods. Curves show the increase in absorbance values (OD) after addition of DTT. For comparison is shown the corresponding control experiment with vehicle only (0, black line). ( C ) Kinetics of dieosin glutathione disulfide (Di-E-GSSG) reduction into fluorescent EGSH catalyzed by ERp57 (20 nM) in the presence of different concentrations (1, 5 and 10 μg/ml) of TIZ or vehicle (0). Data are expressed as arbitrary fluorescence units (AFU). ( D ) The effect of TIZ (10 μg/ml) was evaluated in the di-eosin-GSSG assay using increasing concentrations of substrate (Di-E-GSSG). Michaelis–Menten kinetics were evaluated using GraphPad Prism 5.0 and compared with vehicle only (DMSO). ( E ) Lineweaver-Burk plot of the inhibition of ERp57 disulfide-reductase activity by TIZ (10 μg/ml), at increasing concentrations of Di-E-GSSG. ( F ) Reversibility of ERp57 inhibition by TIZ. ERp57 (400 nM) was incubated with 10 μg/ml TIZ for 15 min, and subsequently diluted 20 times into reaction buffer (TIZ-r). Di-E-GSSG reduction was compared with samples containing 20 nM ERp57 in the presence of 10 μg/ml TIZ (TIZ) or vehicle ( C ). The TIZ-r curve (blue) shows the rapid recovery of enzymatic activity after dilution, as compared to an undiluted sample (red).

Techniques Used: Activity Assay, Fluorescence, GSSG Assay, Inhibition, Incubation

7) Product Images from "Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats"

Article Title: Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats

Journal: Nutrients

doi: 10.3390/nu9030293


Figure Legend Snippet: Effects of PM on hepatic steatosis in hypercholesterolemic rat. ( A ) Histological analysis of liver tissue in hypercholesterolemic rats. Liver sections were stained with hematoxylin and eosin (H E) and examined under a light microscope ( n = 8 per group); ( B ) Scores of hepatic steatosis of hypercholesterolemic rat livers. Scores were determined according to hepatocytes containing lipid droplets ( n = 8 per group). Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. *** p

Techniques Used: Staining, Light Microscopy


Figure Legend Snippet: Effects of PM treatment on serum levels of ( A ) TC, ( B ) TG, ( C ) LDL-cholesterol, and ( D ) HDL-cholesterol in hypercholesterolemic rats. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. *** p

Figure Legend Snippet: Effects of PM treatment on hepatic cholesterol homeostasis-related proteins in hypercholesterolemic rats. ( A ) Liver extracts from HCD diet, PM, and simvastatin treated groups were used for Western blot analysis; ( B ) Expression levels of SREBP1, FAS, and ACC were quantified by measuring band densities with National Institutes of Health (NIH) Image J software. β-actin was used as a loading control. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # p

Techniques Used: Western Blot, Expressing, Software

8) Product Images from "The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats"

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

Journal: PLoS ONE

doi: 10.1371/journal.pone.0195624


Figure Legend Snippet: Effects of CO and FV mixture treatment on intestine transit length and gastrointestinal transit ratio of constipated rats. Intestine transit length (A) and gastrointestinal transit ratio (B) were observed in 30 min later after receiving barium sulfate. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Figure Legend Snippet: Body weight (BW) changes and feeding behavior during experimental procedure. BW (A) was measured once a week, and food intake (B) and water consumption (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Figure Legend Snippet: Effects of CO and FV mixture treatment on histological properties of transverse colon in constipated rats. H E staining of transverse colon in lop-, CO and FV mixture-, and bis-treated groups (A-F). Scale bar, 100 μm. Mucosa layer (G) and muscular layer (H) thicknesses are presented as graphs. N = 5 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Techniques Used: Staining


Figure Legend Snippet: Effects of CO and FV mixture treatment on mRNA expression of mAchR M2 and M3 in the transverse colon. qRT-PCR analysis of mAchR M2 (A) and M3 (B) mRNA expression. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Techniques Used: Expressing, Quantitative RT-PCR


Figure Legend Snippet: Effects of CO and FV mixture treatment on stool parameters of constipated rats. Stool number (A), stool weight (B), and water contents (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Figure Legend Snippet: The laxative effects of CO and FV treatment on lop-induced constipated rats. Stool number (A), stool weight (B) daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Figure Legend Snippet: Effects of CO and FV mixture treatment on protein expression of mAchR M2 and M3 and PKC and PI3K as their downstream signaling pathway-related proteins in the transverse colon. N = 10 in each group. Western blot analysis of mAchR M2 and M3 (A-C) and phosphorylated and total of PKC and PI3K (D-F) protein expression. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Techniques Used: Expressing, Western Blot

9) Product Images from "Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57"

Article Title: Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

Journal: Scientific Reports

doi: 10.1038/s41598-018-28172-9


Figure Legend Snippet: Tizoxanide inhibits ERp57 activity. ( A ) Domain organization ( top ) and surface representation ( bottom ) of ERp57. ( B ) Effect of tizoxanide (10 and 50 μg/ml) on ERp57 disulfide reductase activity, determined by the insulin reduction turbidometric assay, as described in Methods. Curves show the increase in absorbance values (OD) after addition of DTT. For comparison is shown the corresponding control experiment with vehicle only (0, black line). ( C ) Kinetics of dieosin glutathione disulfide (Di-E-GSSG) reduction into fluorescent EGSH catalyzed by ERp57 (20 nM) in the presence of different concentrations (1, 5 and 10 μg/ml) of TIZ or vehicle (0). Data are expressed as arbitrary fluorescence units (AFU). ( D ) The effect of TIZ (10 μg/ml) was evaluated in the di-eosin-GSSG assay using increasing concentrations of substrate (Di-E-GSSG). Michaelis–Menten kinetics were evaluated using GraphPad Prism 5.0 and compared with vehicle only (DMSO). ( E ) Lineweaver-Burk plot of the inhibition of ERp57 disulfide-reductase activity by TIZ (10 μg/ml), at increasing concentrations of Di-E-GSSG. ( F ) Reversibility of ERp57 inhibition by TIZ. ERp57 (400 nM) was incubated with 10 μg/ml TIZ for 15 min, and subsequently diluted 20 times into reaction buffer (TIZ-r). Di-E-GSSG reduction was compared with samples containing 20 nM ERp57 in the presence of 10 μg/ml TIZ (TIZ) or vehicle ( C ). The TIZ-r curve (blue) shows the rapid recovery of enzymatic activity after dilution, as compared to an undiluted sample (red).

Techniques Used: Activity Assay, Fluorescence, GSSG Assay, Inhibition, Incubation

10) Product Images from "Key structural features for substrate binding to organic anion transporter 1 (Oat1; slc22a6) identified by global untargeted metabolomics of Oat1null plasma"

Article Title: Key structural features for substrate binding to organic anion transporter 1 (Oat1; slc22a6) identified by global untargeted metabolomics of Oat1null plasma

Journal: Journal of proteome research

doi: 10.1021/pr200093w


Figure Legend Snippet: Interactions of metabolomic metabolites with mOat1 A number of metabolites were identified by non-targeted metabolomics and several (i.e., indoxyl sulfate, xanthurenic acid and kynurenine) were tested for Oat1-mediated handling in vitro utilizing microinjected Xenopus oocytes (3–4 different concentrations ranging from 10μm to 10mm were employed). Curves were plotted using non-linear regression with Prism software 5.0 and IC50 values were calculated (GraphPad Inc., San Diego, CA). Each data point represents the mean ± S.E values of four groups of 4 oocytes each. All the tested compounds showed strong inhibition of uptake of fluorescent tracer (6-carboxyfluoroscein) and interacted strongly with mOat1 transporter.

Techniques Used: In Vitro, Software, Inhibition

11) Product Images from "Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis *Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis * S⃞"

Article Title: Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis *Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis * S⃞

Journal: The Journal of Biological Chemistry

doi: 10.1074/jbc.M806943200


Figure Legend Snippet: Enzymatic properties of glycosylated and Endo H-deglycosylated TPP1. CHO cell-produced enzyme preparations described in Fig. 1 were incubated at pH 3.5 for 2 h at 37 °C. Enzyme activity measurements were conducted using eight different concentrations of either Ala-Ala-Phe-AMC (800 to 6.25 μ m ) or Arg-Nle-Nle-AMC (400 to 3.12 μ m ) substrate. Final reactions contained 150 m m NaCl, 0.1% Triton X-100, and either 100 m m sodium formate, pH 2.5, or sodium acetate (all other pH values) adjusted to the indicated pH using HCl. Kinetic constants were calculated using the built-in Michaelis-Menten curve fitting functions in Prism version 5.01. Open symbols denote deglycosylated protein; filled symbols denote glycosylated protein. A and B, circles, k cat ; squares, K m . C, circles , Ala-Ala-Phe-AMC substrate; squares , Arg-Nle-Nle-AMC substrate.

Techniques Used: Produced, Incubation, Activity Assay

12) Product Images from "Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters *"

Article Title: Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters *

Journal: The Journal of Biological Chemistry

doi: 10.1074/jbc.M114.625343


Figure Legend Snippet: Na + -dependent [ 3 H]DA uptake by DAT-WT and the DAT-R60A, DAT-Y335A, and DAT-D436A mutants. [ 3 H]DA uptake by DAT-WT (■) is increased with increasing [Na + ] and reaches saturation with an EC 50 = 27 ± 2 m m Na + and a Hill slope of 2.0 ± 0.23 ( n = 6). [ 3 H]DA uptake by DAT-R60A (▵) and DAT-D436A (▿) exhibits Na + dependence indistinguishable from WT traces ( n = 7 and 3, respectively). The uptake by DAT-Y335A (○) also increases with increasing [Na + ] but does not saturate within the range of tested Na + concentrations ( n = 4). To obtain a constant ionic strength in the uptake buffer, the NaCl is titrated against choline chloride. Data are means ± S.E. ( error bars ) of experiments performed in triplicate on COS7 cells transiently expressing DAT-WT or the indicated mutations herein and normalized to their respective uptake in 200 m m Na + . Kinetic constants were determined using a single-site fitting model in GraphPad Prism version 5.0.

Techniques Used: Expressing

13) Product Images from "The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats"

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

Journal: PLoS ONE

doi: 10.1371/journal.pone.0195624


Figure Legend Snippet: Effects of CO and FV mixture treatment on intestine transit length and gastrointestinal transit ratio of constipated rats. Intestine transit length (A) and gastrointestinal transit ratio (B) were observed in 30 min later after receiving barium sulfate. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Figure Legend Snippet: Body weight (BW) changes and feeding behavior during experimental procedure. BW (A) was measured once a week, and food intake (B) and water consumption (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Figure Legend Snippet: Effects of CO and FV mixture treatment on histological properties of transverse colon in constipated rats. H E staining of transverse colon in lop-, CO and FV mixture-, and bis-treated groups (A-F). Scale bar, 100 μm. Mucosa layer (G) and muscular layer (H) thicknesses are presented as graphs. N = 5 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Techniques Used: Staining


Figure Legend Snippet: Effects of CO and FV mixture treatment on mRNA expression of mAchR M2 and M3 in the transverse colon. qRT-PCR analysis of mAchR M2 (A) and M3 (B) mRNA expression. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Techniques Used: Expressing, Quantitative RT-PCR


Figure Legend Snippet: Effects of CO and FV mixture treatment on stool parameters of constipated rats. Stool number (A), stool weight (B), and water contents (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Figure Legend Snippet: The laxative effects of CO and FV treatment on lop-induced constipated rats. Stool number (A), stool weight (B) daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Figure Legend Snippet: Effects of CO and FV mixture treatment on protein expression of mAchR M2 and M3 and PKC and PI3K as their downstream signaling pathway-related proteins in the transverse colon. N = 10 in each group. Western blot analysis of mAchR M2 and M3 (A-C) and phosphorylated and total of PKC and PI3K (D-F) protein expression. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Techniques Used: Expressing, Western Blot

14) Product Images from "In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays"

Article Title: In Vitro Activity of Ceftazidime-Avibactam Combination in In Vitro Checkerboard Assays

Journal: Antimicrobial Agents and Chemotherapy

doi: 10.1128/AAC.04146-14


Figure Legend Snippet: Cumulative % inhibition of 18 P. aeruginosa isolates by ceftazidime for increasing concentrations (symbols below the figure, mg/liter) of avibactam. The % inhibition of growth of P. aeruginosa is presented on the y axis with the MIC for ceftazidime on the x axis as related to the added concentrations of avibactam in differently colored lines.

Techniques Used: Inhibition

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Journal: Journal of Virology

Article Title: A Mutant of Sindbis Virus Which Is Able To Replicate in Cells with Reduced CTP Makes a Replicase/Transcriptase with a Decreased Km for CTP

doi: 10.1128/JVI.78.18.9645-9651.2004

Figure Lengend Snippet: Kinetic analyses of in vitro viral RNA synthesis by the SV CPC and SV STD replicase/transcriptases. The assays were performed with p15 fractions from virus-infected mosquito cells as described in Materials and Methods. Nonlinear regression analysis with the GraphPad Prism version 3.0 software was used to calculate the K m s of the SV polymerase for CTP (A) and UTP (B). Each reaction was done in triplicate.

Article Snippet: The Km values were calculated with (., San Diego, Calif.).

Techniques: In Vitro, Infection, Software

Journal: British Journal of Clinical Pharmacology

Article Title: The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver

doi: 10.1046/j.1365-2125.2002.01614.x

Figure Lengend Snippet: Spearman rank correlation between CYP2C9 (a), CYP2D6 (b), CYP2B6 (c) and CYP3A4 (d) expression (pmol mg −1 protein) and formation rate of Z-4-OH-tamoxifen ( V , pmol mg −1 protein min −1 ) in human liver microsomes ( n = 50).

Article Snippet: Estimates of intrinsic clearance (µl min−1 pmol−1 P450) by a particular CYP isoform were obtained from the slope of the linear regression of the formation rates against the initial (Prism®, Version 3.0, ., San Diego, CA, USA).

Techniques: Expressing

Journal: Nutrients

Article Title: Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats

doi: 10.3390/nu9030293

Figure Lengend Snippet: Effects of PM on hepatic steatosis in hypercholesterolemic rat. ( A ) Histological analysis of liver tissue in hypercholesterolemic rats. Liver sections were stained with hematoxylin and eosin (H E) and examined under a light microscope ( n = 8 per group); ( B ) Scores of hepatic steatosis of hypercholesterolemic rat livers. Scores were determined according to hepatocytes containing lipid droplets ( n = 8 per group). Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. *** p

Article Snippet: Statistical significance was analyzed by using repeated measures or one-way ANOVA with (Prism 5.0.3, ., San Diego, CA, USA).

Techniques: Staining, Light Microscopy

Journal: Nutrients

Article Title: Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats

doi: 10.3390/nu9030293

Figure Lengend Snippet: Effects of PM treatment on serum levels of ( A ) TC, ( B ) TG, ( C ) LDL-cholesterol, and ( D ) HDL-cholesterol in hypercholesterolemic rats. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. *** p

Article Snippet: Statistical significance was analyzed by using repeated measures or one-way ANOVA with (Prism 5.0.3, ., San Diego, CA, USA).

Techniques:

Journal: Nutrients

Article Title: Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats

doi: 10.3390/nu9030293

Figure Lengend Snippet: Effects of PM treatment on hepatic cholesterol homeostasis-related proteins in hypercholesterolemic rats. ( A ) Liver extracts from HCD diet, PM, and simvastatin treated groups were used for Western blot analysis; ( B ) Expression levels of SREBP1, FAS, and ACC were quantified by measuring band densities with National Institutes of Health (NIH) Image J software. β-actin was used as a loading control. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # p

Article Snippet: Statistical significance was analyzed by using repeated measures or one-way ANOVA with (Prism 5.0.3, ., San Diego, CA, USA).

Techniques: Western Blot, Expressing, Software

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: Effects of CO and FV mixture treatment on intestine transit length and gastrointestinal transit ratio of constipated rats. Intestine transit length (A) and gastrointestinal transit ratio (B) were observed in 30 min later after receiving barium sulfate. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques:

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: Body weight (BW) changes and feeding behavior during experimental procedure. BW (A) was measured once a week, and food intake (B) and water consumption (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques:

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: Effects of CO and FV mixture treatment on histological properties of transverse colon in constipated rats. H E staining of transverse colon in lop-, CO and FV mixture-, and bis-treated groups (A-F). Scale bar, 100 μm. Mucosa layer (G) and muscular layer (H) thicknesses are presented as graphs. N = 5 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ## P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques: Staining

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: Effects of CO and FV mixture treatment on mRNA expression of mAchR M2 and M3 in the transverse colon. qRT-PCR analysis of mAchR M2 (A) and M3 (B) mRNA expression. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. ### P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques: Expressing, Quantitative RT-PCR

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: Effects of CO and FV mixture treatment on stool parameters of constipated rats. Stool number (A), stool weight (B), and water contents (C) were daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques:

Journal: PLoS ONE

Article Title: The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats

doi: 10.1371/journal.pone.0195624

Figure Lengend Snippet: The laxative effects of CO and FV treatment on lop-induced constipated rats. Stool number (A), stool weight (B) daily measured in each group. N = 10 in each group. Data are expressed as mean ± SEM. Significance was measured by performing a one-way ANOVA followed by Bonferroni’s post-hoc test. # P

Article Snippet: Statistical significance was analyzed using one-way ANOVA with (Prism 5.0.3, ., San Diego, USA).

Techniques:

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* Corresponding authors

a Farmacognosia, Departamento de Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina
E-mail:rfurlan@fbioyf.unr.edu.ar

b Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN, CONICET-UBA), Departamento de Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Intendente Guiraldes 2160, Ciudad Autónoma de Buenos Aires C1428EGA, Argentina

c Instituto de Química Rosario (IQUIR, CONICET-UNR), Área Química General e Inorgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina

d Instituto de Fisiología Experimental (IFISE, CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina

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